Pre-Workout may shield muscles from bed rest damage

NCT ID NCT06205784

Completed Knowledge-focused Sponsor: Bispebjerg Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether doing heavy resistance exercise before a period of leg immobilization can prevent muscle loss. 48 healthy adults (young and older) will have one knee immobilized for 7-10 days, then undergo 4 weeks of retraining. Half will also exercise for 4 weeks before immobilization. Researchers will measure muscle size, fiber changes, and protein synthesis to understand protective effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: heavy resistance exercise
What this could lead to: If it works, this could point toward exercise strategies to prevent muscle loss during periods of inactivity, like after injury or surgery.
What could go wrong: This is a small, early-stage study in healthy people, not patients. Results may not apply to those with muscle diseases or injuries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DISUSE ATROPHY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

muscular atrophy Muscular Disorders, Atrophic Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DISUSE ATROPHY SARCOPENIA SKELETAL MUSCLE ATROPHY

Contacts and locations

Show contact details

Locations

Institute of Sports Medicine Copenhagen

Copenhagen, Capital Region, 2400, Denmark

More trials for these conditions

Other studies related to the condition(s) this trial covers.