Cure My Disease

Don't miss your cure!

 Log in / Sign up

Pre-Workout may shield muscles from bed rest damage

NCT ID NCT06205784

Knowledge-focused Sponsor: Bispebjerg Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether doing heavy resistance exercise before a period of leg immobilization can prevent muscle loss. 48 healthy adults (young and older) will have one knee immobilized for 7-10 days, then undergo 4 weeks of retraining. Half will also exercise for 4 weeks before immobilization. Researchers will measure muscle size, fiber changes, and protein synthesis to understand protective effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
heavy resistance exercise
What this could lead to
If it works, this could point toward exercise strategies to prevent muscle loss during periods of inactivity, like after injury or surgery.
What could go wrong
This is a small, early-stage study in healthy people, not patients. Results may not apply to those with muscle diseases or injuries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

64 people

The number who actually took part.

Started

Jan 2024

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 85 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age: Between 20-35 years old or between 65-85 years old. * BMI: Between 18.5 and 35 kg/m2. * Healthy and well, with normal dietary habits (not vegan). Exclusion Criteria: * More than one muscle biopsy previously taken from both vastus lateralis muscles. * Smoking. * Pregnancy. * Past or present substance or alcohol abuse. * Medical/surgical conditions that are assessed to affect protein synthesis or the participant's involvement in the trial. * Knee pain that could affect the completion of the training intervention. * High intake of supplements that increase the risk of bleeding during muscle biopsy (such as fish oil and ginger). * Participation in regular strength training within the past year. * Regular participation in structured sports. * Current use of blood-thinning medication. * Previous participation in trials involving oral intake of heavy water. * Metal in the body preventing MRI scanning. * For the older group, not having gone through menopause, and for the younger group, not having a regular menstrual cycle.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Disuse atrophy are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

muscular atrophy Muscular Disorders, Atrophic Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Disuse atrophy Sarcopenia Skeletal muscle atrophy

Contacts and locations

Locations

  • Institute of Sports Medicine Copenhagen

    Copenhagen, Capital Region, 2400, Denmark

More trials for these conditions

Other studies related to the condition(s) this trial covers.