Could a brain hormone curb heavy drinking? new trial aims to find out.
NCT ID NCT05781009
First seen Feb 02, 2026 · Last updated May 13, 2026 · Updated 13 times
Summary
This study tests whether a natural hormone called pregnenolone can help people with alcohol use disorder drink less. About 150 adults who drink heavily at least 3 times a week will take either pregnenolone or a placebo daily for 12 weeks. Researchers will track heavy drinking days and side effects to see if the treatment is safe and effective.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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The Yale Stress Center: Yale University
RECRUITINGNew Haven, Connecticut, 06519, United States
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