New combo therapy aims to slash opioid use in injury patients

NCT ID NCT04705480

First seen Jan 07, 2026 · Last updated May 11, 2026 · Updated 22 times

Summary

This study tested whether adding pregabalin or gabapentin to standard opioid painkillers could reduce the amount of opioids needed by adults hospitalized with orthopedic injuries. 109 participants were randomly assigned to receive one of the two nerve-pain medications alongside their usual care. The goal was to see if this approach could lower opioid use and potentially reduce side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PAIN are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Charleston Area Medical Center"s Level 1 Trauma Center

    Charleston, West Virginia, 25301, United States

Conditions

Explore the condition pages connected to this study.