Brain scans may forecast recovery in coma patients

NCT ID NCT04692922

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study aims to develop a tool that predicts recovery in people with severe brain injury who are in a coma or minimally conscious state. Researchers will use MRI and EEG scans, along with other clinical factors, to build an algorithm. The goal is to forecast how well patients will recover 6 months after their injury. The study will enroll 50 adults at Massachusetts General Hospital.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a tool that helps doctors predict how well a patient with severe brain injury might recover, aiding in treatment decisions.
What could go wrong
This is an early observational study with only 50 participants, so the algorithm may not be accurate for all patients. It does not test a treatment, so it won't directly improve outcomes.

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Conditions

The condition(s) this trial relates to.

Consciousness Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.