A new study mines health data to spot painkiller dependence early
NCT ID NCT03684317
First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time
Summary
This study investigates whether early changes in how people use painkillers can predict who will develop dependence, even without a prior history of addiction. Researchers will analyze a large French national health database, focusing on adults who are new users of analgesic drugs. By tracking their prescriptions and any related complications over time, the study aims to identify warning signs that could help healthcare providers intervene sooner.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors identify patients at risk of becoming dependent on painkillers before problems start, enabling earlier prevention and safer prescribing.
- What could go wrong
- This is an observational study using existing health records, so it can show patterns but not prove cause and effect. The findings may not apply to all populations or healthcare systems.
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Study facts
What this study's own registry entry says, in plain language.
- Started
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Jun 2019
- Finished
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Apr 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Subjects included in the SNIIRAM database (affiliated to the 3 French main Insurance Scheme)
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Subjects included in the SNIIRAM (French National inter-scheme health insurance information system) database * Age \>18 at index date (date of first analgesic dispensing) * At least three dispensing of analgesic drugs * At least two years of available follow-up at the date of first analgesic dispensing in the SNIIRAM database * No dispensing for any of the analgesics of interest in the past 12 months (selection of new users only) Exclusion Criteria: * none
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Hospital toulouse
Toulouse, France
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