10,000 relatives to be tracked for early Crohn's warning signs

NCT ID NCT07316621

Recruiting now Knowledge-focused Sponsor: GLSMED Learning Health S.A. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 30, 2026 · Updated 3 times

Summary

This study aims to develop a risk score for Crohn's disease by following 10,000 first-degree relatives (parents, siblings, or children) of people with Crohn's. Participants aged 16 to 35 will give blood and stool samples and answer lifestyle questionnaires every six months. The goal is to see if combining blood markers with lifestyle factors can predict who will develop the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a way to identify people at high risk for Crohn's disease before symptoms start, enabling early monitoring or prevention strategies.
What could go wrong: This is an observational study, not a treatment trial. The risk score may not accurately predict disease, and results may take years to confirm.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CROHN DISEASE (CD) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Crohn disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CROHN DISEASE (CD)

Contacts and locations

Show contact details

Locations

AUMC
RECRUITING

Amsterdam, Netherlands
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
RECRUITING

Roma, Italy
Hospital Beatriz Ângelo
RECRUITING

Lisbon, Portugal
Hospital Galdakao-Usansolo
RECRUITING

Galdakao, Spain
Hospital Santa Maria
RECRUITING

Lisbon, Portugal
Hospital da Luz Lisboa
RECRUITING

Lisbon, Portugal
Hospital dos Capuchos
RECRUITING

Lisbon, Portugal

Contact Email: •••••@•••••
Państwowy Instytut Medyczny MSWiA w Warszawie
RECRUITING

Warsaw, Poland
UMCG
RECRUITING

Groningen, Netherlands
Örebro University Hospital
RECRUITING

Örebro, Sweden

More trials for these conditions

Other studies related to the condition(s) this trial covers.