Tailored muscle cuts for swallowing disorders: a precision medicine trial

NCT ID NCT07293689

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study observes how doctors decide the length of the muscle cut during POEM surgery for people with swallowing disorders like achalasia. Researchers will follow 200 adults for 2 years, tracking symptoms and whether retreatment is needed. The goal is to see if tailoring the surgery to each patient's condition leads to better outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could show that tailoring the length of the muscle cut during POEM surgery leads to better, more personalized treatment for swallowing disorders.

What could go wrong

This is an observational study, not a test of a new treatment. It only looks at how doctors currently decide, so it won't prove that one method is better than another.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

achalasia dyskinesia of esophagus Esophageal Achalasia idiopathic achalasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Adventist Health System/Sunbelt, Inc

    NOT_YET_RECRUITING

    Orlando, Florida, 32803, United States

  • Baylor Scott & White Health

    NOT_YET_RECRUITING

    Dallas, Texas, 75204, United States

  • Case Western Reserve University

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44106, United States

  • Emory University

    NOT_YET_RECRUITING

    Atlanta, Georgia, 30322, United States

  • Johns Hopkins University

    NOT_YET_RECRUITING

    Baltimore, Maryland, 21218, United States

  • Mayo Clinic Arizona

    NOT_YET_RECRUITING

    Scottsdale, Arizona, 85259, United States

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of California San Diego

    NOT_YET_RECRUITING

    La Jolla, California, 92093, United States

  • University of Colorado Denver

    NOT_YET_RECRUITING

    Denver, Colorado, 80217, United States

  • University of Florida

    NOT_YET_RECRUITING

    Gainesville, Florida, 32611, United States

  • Vanderbilt University Medical Center

    NOT_YET_RECRUITING

    Nashville, Tennessee, 37232, United States

  • Washington University

    NOT_YET_RECRUITING

    St Louis, Missouri, 63130, United States

  • Weill Cornell Medical College

    NOT_YET_RECRUITING

    New York, New York, 10065, United States