Gene test could personalize heart drug treatment

NCT ID NCT07408427

First seen Feb 16, 2026 · Last updated May 23, 2026 · Updated 18 times

Summary

This study looks at why the heart drug mavacamten works better for some people with hypertrophic cardiomyopathy (a condition where the heart muscle thickens). Researchers will check if a person's specific gene causing HCM and their natural ability to process medications (via the CYP2C19 gene) affect the drug's performance. About 140 adults with obstructive HCM will participate to help tailor future treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HYPERTROPHIC CARDIOMYOPATHY (HCM) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Manchester Centre for Genomic Medicine (MCGM)

    Multiple Locations, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.