Nose spray before surgery may ease After-Surgery behavior in kids with autism
NCT ID NCT07324057
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if giving a sedative nose spray (dexmedetomidine or esketamine) before anesthesia can reduce negative behavior changes like sleep problems or anxiety in children with autism after surgery. About 234 children aged 2-12 will be randomly assigned to receive one of the two medicines or a saltwater spray. Researchers will check behavior at 3, 7, and 28 days after surgery to see if either medicine helps compared to the placebo.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Children's Hospital of Nanjing Medical University
RECRUITINGNanjing, Jiangsu, 210000, China
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