Nose spray before surgery may ease After-Surgery behavior in kids with autism
NCT ID NCT07324057
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if giving a sedative nose spray (dexmedetomidine or esketamine) before anesthesia can reduce negative behavior changes like sleep problems or anxiety in children with autism after surgery. About 234 children aged 2-12 will be randomly assigned to receive one of the two medicines or a saltwater spray. Researchers will check behavior at 3, 7, and 28 days after surgery to see if either medicine helps compared to the placebo.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Children's Hospital of Nanjing Medical University
RECRUITINGNanjing, Jiangsu, 210000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••