Extra 6-Minute MRI scan may guide robotic tonsil cancer surgery

NCT ID NCT07060261

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether adding a short MRI scan before surgery can help predict if all cancer will be removed during transoral robotic surgery (TORS) for HPV-positive tonsil cancer. About 30 adults will get a standard MRI with two extra sequences that take only 6 minutes. Doctors will then compare the MRI results to the actual surgical margins to see if the scan can accurately tell if the cancer is fully removed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better plan surgery for HPV+ tonsil cancer, potentially reducing the need for additional treatments.
What could go wrong
This is a small, early-stage study with only 30 participants, so results may not apply to everyone. The MRI technique adds only 6 minutes but may not reliably predict margins.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Case Comprehensive Cancer Center, Cleveland Clinic Foundation

    RECRUITING

    Cleveland, Ohio, 44195, United States

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