Can adding radiation before surgery boost immune response in aggressive breast cancer?

NCT ID NCT07276880

First seen Jan 06, 2026 · Last updated May 09, 2026 · Updated 15 times

Summary

This study is for people with operable, lymph node-positive triple negative breast cancer. It tests whether giving a low or high dose of radiation to the breast tumor along with immunotherapy (pembrolizumab) before standard chemotherapy can improve the chance of eliminating all cancer in the lymph nodes at surgery. About 32 participants will be randomly assigned to receive either low or high dose radiation over 3 days, followed by standard treatment and surgery.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of North Carolina

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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