New hope for hepatitis b: Real-World trial of pradefovir underway
NCT ID NCT07555340
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing a drug called pradefovir mesylate in 400 adults with chronic hepatitis B. The goal is to see how well it lowers the virus and how safe it is in everyday medical practice, not just in a strict research setting. Participants are being followed for up to 65 weeks to check if the virus becomes undetectable.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
pradefovir mesylate tablets
What this could lead to
If successful, this could confirm pradefovir as a safe and effective antiviral option for controlling chronic hepatitis B, potentially reducing liver damage and transmission risk.
What could go wrong
This is an observational real-world study, not a randomized controlled trial, so results may be less definitive. The drug may not work for all patients or could have side effects not fully captured.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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The First Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, 450000, China