New drug trial aims to tame muscle weakness in myasthenia gravis

NCT ID NCT07501702

Recruiting now Disease control Sponsor: Vertex Pharmaceuticals Incorporated Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 04, 2026 · Updated 6 times

Summary

This study tests an experimental drug called povetacicept in adults with generalized myasthenia gravis, a condition that causes muscle weakness. The goal is to see if the drug safely reduces harmful immune proteins. About 30 participants will receive either the drug or a placebo, and researchers will monitor side effects and immune changes.

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Conditions

The condition(s) this trial relates to.

myasthenia gravis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MYASTHENIA GRAVIS, GENERALIZED

Contacts and locations

Locations

Centrum Medyczne Neuroprotect
RECRUITING

Warsaw, Poland
Clinical Research Center Sp. z o.o., Medic-R Sp. K.
RECRUITING

Poznan, Poland
Clinical Trials of South Carolina - Neurology
RECRUITING

Charleston, South Carolina, 29406, United States
ETG Neuroscience
RECRUITING

Warsaw, Poland
Eastern Health - Box Hill Hospital
RECRUITING

Box Hill, Australia
HSHS Medical Group - St. Elizabeth's Hospital
RECRUITING

O'Fallon, Illinois, 62269, United States
Hawaii Pacific Neuroscience
RECRUITING

Honolulu, Hawaii, 96817, United States
Homestead Associates in Research
RECRUITING

Homestead, Florida, 33033, United States
Las Vegas Neurology Center
RECRUITING

Las Vegas, Nevada, 89106, United States
MICS Centrum Medyczne Bydgoszcz
RECRUITING

Bydgoszcz, Poland
NZOZ NEURO-KARD Ilkowski i Partnerzy Sp. Partnerska Lekarzy
RECRUITING

Poznan, Poland
Nerve and Muscle Center of Texas - Neurology
RECRUITING

Houston, Texas, 77030, United States
Neurologia Slaska Centrum Medyczne
RECRUITING

Katowice, Poland
Neurology Care Clinic
RECRUITING

Waxahachie, Texas, 75165, United States
Neurology Offices
RECRUITING

Boca Raton, Florida, 33428, United States
Northern Care Alliance NHS Foundation Trust - Salford Royal Hospital
RECRUITING

Salford, United Kingdom
Quantix Research
RECRUITING

Miami, Florida, 33173, United States
SFM Clinical Reseach, LLC
RECRUITING

Boca Raton, Florida, 33487, United States
St. George's University Hospital
RECRUITING

London, United Kingdom
Texas Institute for Neurological Disorders
RECRUITING

Sherman, Texas, 75093, United States
Tri Valley Neurology Medical Associates Inc.
RECRUITING

Mission Hills, California, 91345, United States
Twoja Przychodnia Poznanskie Centrum Medyczne Sp. z o. o.
RECRUITING

Poznan, Poland
UF Health Jacksonville Respiratory Therapy (PFT and DLCO)
RECRUITING

Jacksonville, Florida, 32209, United States
University Hospitals Birmingham NHS Foundation Trust - Queen Elizabeth Hospital
RECRUITING

Birmingham, United Kingdom
Ut Erlanger Neurology
RECRUITING

Chattanooga, Tennessee, 37403, United States
Y & L Advance Health Care, Inc D/B/A Elite Clinical Research - Neurology
RECRUITING

Miami, Florida, 33144, United States

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