New drug aims to ease daily struggles of myasthenia gravis

NCT ID NCT07647510

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial tests whether claseprubart (DNTH103) can improve symptoms of generalized myasthenia gravis, a condition causing muscle weakness. About 195 adults with a specific antibody type are randomly assigned to receive the drug or a placebo. The main goal is to see if the drug helps with daily activities and muscle strength over 17 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

claseprubart (DNTH103)

What this could lead to

If successful, this could provide a new treatment option for people with generalized myasthenia gravis, potentially improving their ability to perform daily activities and muscle strength.

What could go wrong

This is a phase 3 trial, but results may not confirm benefit or could show side effects. The drug is still investigational and not yet approved.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

myasthenia gravis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••