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Gut health for the mind: postbiotics tested as mood boosters

NCT ID NCT06982599

Symptom relief Sponsor: Hanyang University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking postbiotics (a dietary supplement) for 8 weeks can reduce depressive symptoms and improve mood in Korean adults aged 19-39 with mild to moderate mood issues. Fifty-two participants will receive either postbiotics or a placebo, and their mood will be tracked using questionnaires and real-time surveys. The goal is to see if this gut-related supplement offers a simple way to ease mood problems.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
postbiotics (dietary supplement)
What this could lead to
If it works, this could point toward a simple, over-the-counter supplement to help manage mild mood symptoms.
What could go wrong
This is a small, early-stage trial with only 52 participants. The effect may be small or no better than placebo, and results may not apply to other populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 52 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 to 39 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged between 19 and 39 years at the time of screening. * BMI between 18.5 and 30 at the time of screening. * CES-D (Center for Epidemiologic Studies Depression Scale) score of 16 or higher. * Ability to access and respond to the survey via an online link. Exclusion Criteria: * Participation in any human clinical trial within the past 3 months before screening. * History of antipsychotic medication treatment within the past 3 months before screening. * Presence of chronic diseases, including cardiovascular, endocrine, immune, respiratory, hepatobiliary, renal and urological, neurological, musculoskeletal, inflammatory, hematological, oncological, or gastrointestinal disorders. * Use of medications or health supplements related to gut health and mood disorders (e.g., antibiotics, laxatives, antidiarrheals, prebiotics, probiotics, postbiotics, anxiolytics, antidepressants, etc.) within 1 month prior to participation in the study. * History of significant hypersensitivity to postbiotics or starch. * Alcohol addiction, drug abuse, or suspicion of substance misuse. * Pregnant or breastfeeding women. * Any other reasons that the study investigator deems the participant unsuitable for participation.

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Conditions

The condition(s) this trial relates to.

mood disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Mood disorder

Contacts and locations

Locations

  • Hanyang University

    Seoul, Seoul, 04763, South Korea

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