Could a postbiotic ease severe IBS diarrhea? new trial results in
NCT ID NCT06346847
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a postbiotic supplement can reduce belly pain and other symptoms in people with moderate to severe diarrhea-predominant irritable bowel syndrome (IBS-D). 384 adults aged 18 to 55 took either the postbiotic or a placebo for 12 weeks, then stopped for 3 weeks. The main goal was to see if more people felt at least a 50-point improvement on a symptom severity scale. The trial also checked effects on anxiety, mood, and stress.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Anand Multispeciality Hospital
Vadodara, Gujarat, 390016, India
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Apollo Hospital
Navi Mumbai, Maharashtra, 400614, India
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Asian Institute of Medical sciences
Thane, Maharashtra, 421203, India
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Astha Clinic
Nashik, Maharashtra, 422011, India
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Astha Clinic
Nashik, India
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Birch Multispeciality Hospital
Maharashtra, 411041, India
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Criticare Asia Multispeciality Hospital & Research Centre
Mumbai, Maharashtra, 400069, India
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Ford Hospital
Uttar Pradesh, 221005, India
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GCS Medical College, Hospital & Research Centre
Gujarat, 380025, India
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Gastrohub Hospital
Pune, Maharashtra, 411027, India
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HCG Hospital
Ahmedabad, Gujarat, 380006, India
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Human care hospital
Uttar Pradesh, 226012, India
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Lifeline Multispeciality Hospital
Pune, Maharashtra, 412101, India
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Lifeline multispeciality hospital
Maharashtra, 412101, India
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Maharaja Agrasen Superspeciality Hospital
Jaipur, Rajasthan, 302039, India
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Maharaja Agrasen Superspeciality Hospital
Jaipur, India
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Mata Roop Rani Maggo Hospital & IVF Center
New Delhi, 110059, India
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Nand Hospital
Gujarat, 390015, India
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Samvedna Hospital
Varanasi, Uttar Pradesh, 221005, India
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Stress Test Clinic
Mumbai, Maharashtra, 400059, India
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Surya Multispeciality Hospital
Nashik, Maharashtra, 422003, India
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Swara Hospital
Pālghar, Maharashtra, 401303, India
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Umarji Mother and Child Care Hospital
Pune, Maharashtra, 411045, India
More trials for these conditions
Other studies related to the condition(s) this trial covers.