Herbal tablet aims to calm IBS-Related diarrhea and pain

NCT ID NCT05687435

Completed Disease control Sponsor: Mei Han Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This trial tests whether the Chinese herbal tablet Changyanning can reduce diarrhea and abdominal pain in people with diarrhea-predominant irritable bowel syndrome (IBS-D). About 240 adults aged 18 to 65 with moderate to severe symptoms will receive either the herbal tablet or a placebo for several weeks. The study measures how many people have at least a 30% drop in pain and fewer days with loose stools.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: a Chinese herbal tablet called Changyanning, made from Euphorbia humifusa, golden ear grass, camphor tree root, Elsholtzia splendens, and maple leaves
What this could lead to: If it works, this could offer a new herbal treatment option for managing diarrhea and abdominal pain in IBS-D.
What could go wrong: This is a Phase 4 trial with 240 participants, so results may not apply to everyone. Herbal products can vary in quality and may cause side effects or interact with other medications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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