New drug cocktail aims to stop liver cancer from coming back

NCT ID NCT07160361

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether giving a combination of two drugs—lenvatinib and losartan—after surgery can lower the chance of liver cancer returning in patients whose tumors show 'tumor budding,' a sign of aggressive disease. The drugs work by breaking down collagen barriers around cancer cells and targeting the cells directly. The trial will follow 56 patients for two years to see how many have their cancer come back.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lenvatinib and losartan

What this could lead to

If successful, this combination could offer a new way to reduce the risk of liver cancer returning after surgery for patients with tumor budding.

What could go wrong

This is a small, early-phase study with only 56 participants, so results may not apply to everyone. The combination may cause side effects or fail to prevent recurrence.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••