Antifungal drug fails to show promise in Crohn's Gene-Targeted trial
NCT ID NCT04966585
First seen Feb 24, 2026 · Last updated May 16, 2026 · Updated 12 times
Summary
This study tested the antifungal drug posaconazole in 10 adults with active Crohn's disease who carry a specific genetic risk factor (CARD9 S12N). The goal was to see if reducing gut fungi could improve inflammation and symptoms. The trial was terminated early, so results are limited.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Cedars-Sinai Medical Center (CSMC)
Los Angeles, California, 90048, United States
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Mayo Clinic
Rochester, Minnesota, 55901, United States
Conditions
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