Which painkiller causes less nausea in kids after surgery? a head-to-head trial
NCT ID NCT06186141
First seen Jul 16, 2026 · Last updated Jul 22, 2026 · Updated 3 times
Summary
This trial compares two common painkillers, morphine and oxycodone, given through a patient-controlled pump to children aged 6 to 18 after surgery. The main goal is to see which drug causes less nausea and vomiting, and whether one leads to fewer other side effects like breathing problems. Children are randomly assigned to one of the two drugs, and all other care follows standard hospital routines.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- morphine or oxycodone given intravenously via a patient-controlled analgesia device
- What this could lead to
- If it works, this could help doctors choose the painkiller with fewer side effects for children after surgery.
- What could go wrong
- This is a single-hospital trial, and results may not apply to all children or surgeries. The study focuses on nausea, not overall pain control.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The Royal Children's Hospital
RECRUITINGMelbourne, Victoria, 3052, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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