New hope for myeloma: stem cell transplant vs. drug combo in Head-to-Head trial

NCT ID NCT01745588

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 25 times

Summary

This study tested two ways to use the drug pomalidomide in people with multiple myeloma that had come back or stopped responding to treatment. All 23 participants first received a combination of clarithromycin, pomalidomide, and dexamethasone (ClaPD). Then, half got a stem cell transplant followed by pomalidomide maintenance, while the other half continued ClaPD for more cycles. The goal was to see which approach better controlled the disease.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    Basking Ridge, New Jersey, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Cancer Center @ Suffolk

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Cancer Center at Mercy Medical Center

    Rockville Centre, New York, 11570, United States

  • Memorial Sloan Kettering Cancer Center at Phelps Memorial Hospital Center

    Sleepy Hollow, New York, 10591, United States

  • Memorial Sloan Kettering West Harrison

    Harrison, New York, 10604, United States

  • North Shore LIJ

    New Hyde Park, New York, 11040, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903, United States

  • SUNY Upstate Medical University

    Syracuse, New York, United States

  • Weill Medical College of Cornell University

    New York, New York, United States

Conditions

Explore the condition pages connected to this study.