Polio vaccine showdown: which sequence protects best?
NCT ID NCT07457060
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests two types of inactivated polio vaccine (Sabin strain and wild strain) given in different orders to 480 infants aged 2 months. The goal is to see which sequence triggers the best immune response and causes the fewest side effects. Participants will receive three doses via injection, either into muscle or under the skin.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Inactivated poliovirus vaccine (Sabin strain and wild strain)
What this could lead to
If successful, this could help optimize polio vaccination schedules to improve protection and reduce side effects.
What could go wrong
This is a Phase 4 study, so the vaccines are already approved; the main question is which sequence works best. Results may not apply to all populations.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Centennial Clindev Research and Development of Medical Sciences
RECRUITINGKawit, Cavite, Philippines
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Health Index Multispecialty Clinic - Research and Development on Medical Sciences
RECRUITINGImus, Philippines
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Iloilo Doctors' Hospital
RECRUITINGIloilo City, Philippines
Contact Phone: •••-•••-•••• Email: •••••@•••••