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Polio vaccine showdown: which sequence protects best?

NCT ID NCT07457060

Recruiting now ⭐️ VACCINE ⭐️ Sponsor: Sinovac Biotech Co., Ltd Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two types of inactivated polio vaccine (Sabin strain and wild strain) given in different orders to 480 infants aged 2 months. The goal is to see which sequence triggers the best immune response and causes the fewest side effects. Participants will receive three doses via injection, either into muscle or under the skin.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Inactivated poliovirus vaccine (Sabin strain and wild strain)
What this could lead to
If successful, this could help optimize polio vaccination schedules to improve protection and reduce side effects.
What could go wrong
This is a Phase 4 study, so the vaccines are already approved; the main question is which sequence works best. Results may not apply to all populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

poliomyelitis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POLIOMYELITIS

Contacts and locations

Locations

  • Centennial Clindev Research and Development of Medical Sciences

    RECRUITING

    Kawit, Cavite, Philippines

    Contact Email: •••••@•••••

  • Health Index Multispecialty Clinic - Research and Development on Medical Sciences

    RECRUITING

    Imus, Philippines

  • Iloilo Doctors' Hospital

    RECRUITING

    Iloilo City, Philippines

    Contact Email: •••••@•••••

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