Can toddlers get three vaccines at once? new study says yes

NCT ID NCT06442449

First seen Jan 22, 2026 · Last updated Jun 19, 2026 · Updated 23 times

Summary

This study tested whether giving a booster polio vaccine (sIPV) at the same time as MMR and hepatitis A vaccines is safe and works well in toddlers. About 889 healthy children aged 18 to 22 months who had already received their first polio and MMR shots took part. Researchers checked immune responses and side effects 30 days after vaccination.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Jiangsu Center for Disease Control and Prevention (Jiangsu Institute of Public Health)

    Nanjing, Jiangsu, 210009, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sabin strain inactivated poliovirus vaccine (sIPV), measles-mumps-rubella (MMR) vaccine, and inactivated hepatitis A (HepA-I) vaccine

What this could lead to

If successful, this could show that giving these booster vaccines together is safe and effective, simplifying childhood immunization schedules.

What could go wrong

This is a completed Phase 4 trial, so results are already known. The main risk is that co-administration might lower immune response or increase side effects compared to separate shots.

Conditions

The condition(s) this trial relates to.

hepatitis A virus infection prevention target measles prevention target mumps infectious disease prevention target poliomyelitis prevention target rubella prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.