No-Scalpel fix for swallowing disorder tracked in massive study
NCT ID NCT02770859
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is tracking 5,000 adults with achalasia, a condition where the esophagus fails to relax and push food into the stomach. All participants are treated with POEM, a procedure that uses an endoscope to cut the tight muscle without any incisions on the body. Researchers will measure symptom scores over time to see how well POEM controls the disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
POEM (Per-Oral Endoscopic Myotomy) procedure
What this could lead to
If successful, this could confirm POEM as a reliable, minimally invasive option to control achalasia symptoms and improve swallowing.
What could go wrong
This is an observational registry, not a controlled trial, so results may not prove cause and effect. Risks of POEM include perforation, bleeding, or symptom recurrence.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Indiana University Hospital
Indianapolis, Indiana, 46202-5121, United States