New pill shows promise for rare blood disorder in phase 3 trial

NCT ID NCT06799546

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a new pill called HSK39297 against a standard infusion drug (eculizumab) in 73 adults with paroxysmal nocturnal hemoglobinuria (PNH), a rare blood disorder that destroys red blood cells. Participants had not received prior complement inhibitor treatment. The main goal was to see if the pill could raise hemoglobin levels without needing blood transfusions.

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Conditions

The condition(s) this trial relates to.

paroxysmal nocturnal hemoglobinuria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The First Affiliated Hospital of Nanjing Medical University

    Nanjing, Jiangsu, 210029, China

  • The First Affiliated Hospital, College of Medicine, Zhejiang University

    Hangzhou, Zhejiang, 310003, China