New PNH pill shows promise in Head-to-Head trial

NCT ID NCT06799546

First seen Jan 11, 2026 · Last updated May 13, 2026 · Updated 25 times

Summary

This study tested a new tablet called HSK39297 against the standard drug eculizumab in 73 adults with paroxysmal nocturnal hemoglobinuria (PNH) who had never taken complement inhibitors. The goal was to see if the new pill could raise hemoglobin levels and reduce the need for blood transfusions. Results will show how well it works and how safe it is.

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Contacts and locations

Locations

  • The First Affiliated Hospital of Nanjing Medical University

    Nanjing, Jiangsu, 210029, China

  • The First Affiliated Hospital, College of Medicine, Zhejiang University

    Hangzhou, Zhejiang, 310003, China

Conditions

Explore the condition pages connected to this study.