New hope for PNH patients: early access to danicopan combo therapy
NCT ID NCT05982938
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This program provides early access to danicopan for adults with paroxysmal nocturnal hemoglobinuria (PNH) who have significant extravascular hemolysis (EVH) despite treatment with Soliris or Ultomiris. Participants must be 18 or older, have anemia and high reticulocyte counts, and have failed or cannot use other approved treatments. The goal is to control the disease by reducing red blood cell destruction outside blood vessels.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PAROXYSMAL NOCTURNAL HEMOGLOBINURIA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Research Site
AVAILABLEBologna, 40138, Italy
-
Research Site
AVAILABLECagliari, 09121, Italy
-
Research Site
AVAILABLECatania, 95123, Italy
-
Research Site
AVAILABLECivitanova Marche, 62012, Italy
-
Research Site
AVAILABLECremona, 26100, Italy
-
Research Site
AVAILABLECuneo, 12100, Italy
-
Research Site
AVAILABLEFrosinone, 03100, Italy
-
Research Site
AVAILABLENovara, 28100, Italy
-
Research Site
AVAILABLEPalermo, 90146, Italy
-
Research Site
AVAILABLEPescara, 65100, Italy
-
Research Site
AVAILABLERavenna, 48121, Italy
-
Research Site
AVAILABLEReggio Calabria, 89100, Italy
-
Research Site
AVAILABLERoma, 00161, Italy
-
Research Site
AVAILABLERoma, 00168, Italy
-
Research Site
AVAILABLETorino, 10126, Italy