Could a simple mouth rinse replace invasive tests for a deadly pneumonia?
NCT ID NCT02648256
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a simple mouth rinse could help diagnose Pneumocystis pneumonia, a serious lung infection in people with weakened immune systems. Researchers used a PCR test on the rinse sample to look for the fungus, aiming to find a threshold that indicates active infection. The study involved 408 adults who needed a bronchoscopy for diagnosis, comparing the mouth rinse test to standard methods.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Polymerase Chain Reaction (PCR) on oropharyngeal rinse
What this could lead to
If successful, this could provide a simple, non-invasive way to diagnose Pneumocystis pneumonia quickly, potentially reducing the need for invasive bronchoscopy.
What could go wrong
This is a completed diagnostic study, not a treatment trial. The test may not be accurate enough to replace standard methods, and results may not apply to all patient groups.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PNEUMONIA, PNEUMOCYSTIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
CHU Amiens
Amiens, 80000, France
-
CHU Brest
Brest, 29200, France
-
CHU Rennes
Rennes, 35000, France