Mouthwash may replace painful lung tests for pneumonia diagnosis

NCT ID NCT00342589

First seen Jan 10, 2026 · Last updated May 21, 2026 · Updated 22 times

Summary

This study tested whether a simple saltwater mouth rinse can detect pneumocystis, a lung infection that can be life-threatening for people with weak immune systems (like those with HIV, cancer, or organ transplants). Current diagnosis requires coughing up sputum or a lung scope, which can be uncomfortable and hard to do. The study enrolled over 1,000 participants, including patients with pneumonia and healthy people, to see if new lab techniques can make the oral rinse a reliable diagnostic tool.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.