New gel could help save failing dental implants

NCT ID NCT06914518

Not yet recruiting Disease control Sponsor: Universitat Internacional de Catalunya Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a gel made from polynucleotide and hyaluronic acid can improve treatment for peri-implantitis, a gum infection around dental implants. Thirty-two adults with infected implants will receive standard deep cleaning plus either the gel or a placebo. The main goal is to see if the gel reduces pocket depth around the implant after 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Polynucleotide and hyaluronic acid gel (PN-HA)
What this could lead to: If it works, this gel could improve gum healing around dental implants and reduce the need for more invasive surgery.
What could go wrong: This is a small, early-stage trial with only 32 participants and a short 6-month follow-up. The gel may not provide significant benefit over standard cleaning alone.

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Conditions

The condition(s) this trial relates to.

Peri-Implantitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERI IMPLANTITIS

Contacts and locations

Locations

08195

Sant Cugat del Vallès, Bracelona, 08195, Spain
Clinica Universitaria ́̀ d'Odontologia - UIC Barcelona at the Periodontology Department

Sant Cugat del Vallès, Barcelona, 08195, Spain

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