New gel could boost healing for implant gum disease
NCT ID NCT06914518
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 34 times
Summary
This study tests whether a gel made from polynucleotide and hyaluronic acid can improve the results of non-surgical cleaning for peri-implantitis, a gum infection around dental implants. Thirty-two adults with at least one infected implant and a bone defect will receive the gel or a placebo after cleaning. The main goal is to see if the gel reduces pocket depth around the implant after 6 months.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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08195
Sant Cugat del Vallès, Bracelona, 08195, Spain
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-••••
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Clinica Universitaria ́̀ d'Odontologia - UIC Barcelona at the Periodontology Department
Sant Cugat del Vallès, Barcelona, 08195, Spain
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
polynucleotide and hyaluronic acid gel (PN-HA)
What this could lead to
If it works, this gel could improve healing and reduce pocket depth around infected dental implants, helping to control peri-implantitis without surgery.
What could go wrong
This is a small, early-stage trial with only 32 participants and a 6-month follow-up. The gel may not provide significant benefit over standard cleaning alone, and results may not apply to all implant types.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.