New hope against a silent killer: platform trial aims to slash meningitis deaths

NCT ID NCT06666322

First seen Jan 10, 2026 · Last updated May 01, 2026 · Updated 17 times

Summary

This study tests several new antifungal drug combinations for cryptococcal meningitis, a brain infection that is fatal without treatment and still kills many people with HIV. Researchers will enroll 2,000 adults with HIV and this infection to see which combination works best and has fewer side effects. The goal is to find safer, more effective treatments that are easier to access worldwide.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Infectious Diseases Institute

    RECRUITING

    Kampala, Uganda

    Contact Email: •••••@•••••

  • Mbarara University of Science and Technology

    RECRUITING

    Mbarara, Uganda

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.