Can plasma help heal the brain after injury?

NCT ID NCT06062888

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether giving fresh frozen plasma (FFP) to people with moderate to severe traumatic brain injury can improve their recovery. About 357 adults aged 18-65 will be randomly assigned to receive either standard care alone or standard care plus two units of FFP. Researchers will track safety and outcomes like disability, hospital stay, and brain function up to 6 months later.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fresh frozen plasma (FFP)

What this could lead to

If it works, this could provide a new treatment to improve recovery and reduce disability after traumatic brain injury.

What could go wrong

This is a mid-stage trial, so results are not guaranteed. The treatment may not improve outcomes and carries risks like allergic reactions or infection from plasma.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••