Can a placebo ease a broken heart? scientists investigate
NCT ID NCT04650841
First seen Jan 09, 2026 · Last updated Apr 29, 2026 · Updated 16 times
Summary
This study looks at how the brain's natural painkillers (opioids) influence placebo effects on both physical pain and the pain of social rejection. Sixty adults who recently went through an unwanted breakup will receive either a drug that blocks opioids (naloxone) or a saltwater spray, then undergo brain scans while experiencing painful heat and rejection-related cues. The goal is to understand the brain mechanisms behind placebo effects, not to provide treatment.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dartmouth College
Hanover, New Hampshire, 03755, United States
Contact Email: •••••@•••••
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