PKU Carriers' brains under the microscope: new study seeks answers

NCT ID NCT07220265

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 27 times

Summary

This study looks at adults who carry the gene for phenylketonuria (PKU) but don't have the disease. Researchers want to see if their brains handle phenylalanine differently and if it affects thinking or brain activity. Participants will take phenylalanine or a placebo, then have MRIs and cognitive tests. The goal is to better understand the hidden effects of being a PKU carrier.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Missouri-Columbia

    RECRUITING

    Columbia, Missouri, 65201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.