Scientists hunt for gene clues to sickle cell mysteries

NCT ID NCT03685721

First seen Jun 27, 2026 · Last updated Aug 04, 2026 · Updated 4 times

Summary

This study looks at how differences in the PKLR gene might change sickle cell disease symptoms. Researchers will collect blood samples from 800 adults of African descent, with and without sickle cell disease, to measure certain proteins and energy molecules in red blood cells. The goal is to understand why some people with sickle cell have more complications than others.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

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