Can a new shampoo outsmart dandruff in Hijab-Wearing women?
NCT ID NCT07802808
First seen Sep 03, 2026 · Last updated Sep 04, 2026 · Updated 1 time
Summary
This trial tests whether a shampoo with piroctone olamine can ease seborrheic dermatitis, a common cause of dandruff, in hijab-wearing women. Researchers compare it to a standard ketoconazole shampoo to see which better improves scalp symptoms and skin health. Participants use the assigned shampoo and provide scalp samples to check for changes in microbes and skin moisture. The study aims to offer a safe, effective option for women who cover their hair.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Piroctone olamine 0.75% shampoo, compared against ketoconazole 2% shampoo
- What this could lead to
- If it works, this could offer hijab-wearing women with seborrheic dermatitis a gentler or equally effective alternative to ketoconazole shampoo, with fewer side effects.
- What could go wrong
- This is a small, early-stage comparison. The shampoo may not work as well as ketoconazole, and results may not apply to all women or other forms of dandruff.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
-
86 people
The number who actually took part.
- Started
-
Jan 2026
- Finished
-
Feb 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 59 years
- Sex
-
Female participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Hijab-wearing women with mild, moderate, or severe seborrheic dermatitis. * Aged 18 to 59 years. * Willing to participate in the study and able to provide written informed consent Exclusion Criteria: * Diagnosis of another hair or scalp condition, such as alopecia, trichotillomania, malignancy, or scalp infection, based on medical history. * Current use of medication or treatment for the hair or scalp. * Current use of cytostatic therapy for malignancy or other cytostatic medications. * Known hypersensitivity to the shampoo base or any of its ingredients, based on medical history. * Pregnancy or breastfeeding. * Current use of additional hair or scalp-care products. * History of liver disease, kidney disease, vitiligo, or psoriasis, based on medical history.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
dr. Cipto Mangunkusumo General Hospital
Jakarta, 10430, Indonesia
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