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Pig kidney trial offers hope to thousands waiting for transplants

NCT ID NCT07224763

Recruiting now Disease control Sponsor: United Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a kidney from a genetically modified pig can safely work in people with end-stage renal disease who cannot get a human kidney. Up to 50 participants will receive the pig kidney and be followed for at least 24 weeks to check survival, kidney function, and side effects. If it works, it could offer a new option for those with few alternatives.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
genetically modified pig kidney with thymus tissue
What this could lead to
If successful, this could provide a new source of kidneys for people with end-stage renal disease who have few other options, potentially reducing waitlist deaths.
What could go wrong
This is an early-phase trial with only 50 participants, so results may not apply to everyone. Risks include organ rejection, infections from the pig tissue, and unknown long-term side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ESRD (END STAGE RENAL DISEASE) KIDNEY TRANSPLANTATION XENOTRANSPLANTATION

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • New York University Langone Health

    RECRUITING

    New York, New York, 10016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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