DNA jolt for wrinkles? new trial tests PIEZO-101
NCT ID NCT07671027
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study tests a new treatment called PIEZO-101, a DNA-based biostimulator, for skin aging in the knee and décolleté areas. It is given by injection followed by a mild electric pulse (electroporation) to help it enter skin cells. The trial will enroll 8 healthy women aged 40-65 and focus mainly on safety and how the skin responds.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- PIEZO-101 (a plasmid DNA biostimulator)
- What this could lead to
- If it works, this could point toward a non-surgical treatment for skin aging and wrinkles.
- What could go wrong
- This is a very early, first-in-human trial with only 8 participants. It is designed mainly to check safety, not effectiveness, and may not lead to a real treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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