New pill targets DNA repair in advanced cancers

NCT ID NCT06606990

First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 35 times

Summary

This early study tests a new pill called pidnarulex in 40 people with advanced solid tumors that have spread and stopped responding to standard treatments. The drug blocks a key enzyme cancer cells need to divide and repair their DNA, which may kill them. Researchers will check safety, side effects, and how well the drug works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Cancer Institute Developmental Therapeutics Clinic

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.