Balloons vs. stents: new trial aims to find best treatment for heart blockages
NCT ID NCT06551662
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing whether drug-coated balloons work as well as drug-eluting stents for people with blocked heart arteries. About 321 participants will be randomly assigned to one of three treatments. The main goal is to see how well blood flows through the treated arteries after 6 to 9 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Paclitaxel or Sirolimus drug-coated balloons, or drug-eluting stents
- What this could lead to
- If successful, this could show that drug-coated balloons are a safe and effective alternative to stents for certain types of heart blockages, potentially reducing the need for permanent metal implants.
- What could go wrong
- This is a mid-sized trial, and the results may not apply to all patients. There is a risk that balloons may not keep the artery as open as stents, and long-term outcomes are still unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centre for Heart Disease, University Hospital Wroclaw Department of Heart Disease, Wroclaw Medical University
NOT_YET_RECRUITINGWroclaw, Poland
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Clinical Department of Interventional Cardiology, Medical University of Lublin
NOT_YET_RECRUITINGLublin, Poland
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Department of Cardiology
NOT_YET_RECRUITINGWałbrzych, Poland
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Department of Cardiology and Internal Diseases, Military Institute of Medicine
NOT_YET_RECRUITINGWarsaw, Poland
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Department of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland
NOT_YET_RECRUITINGKatowice, 40-635, Poland
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Department of Cardiology, Copper Health Centre (MCZ)
NOT_YET_RECRUITINGLubin, Poland
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Department of Cardiology, Poznan University of Medical Sciences
NOT_YET_RECRUITINGPoznan, Poland
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Department of Cardiology, The Ministry of Internal Affairs and Administration Hospital, Rzeszow
NOT_YET_RECRUITINGRzeszów, Poland
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Department of Interventional Cardiology, Institute of Cardiology, Jagiellonian University Medical College, Kraków, Poland
NOT_YET_RECRUITINGKrakow, Poland
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Department of Invasive Cardiology, Centre of Postgraduate Medical Education, Central Clinical Hospital of the Ministry of Interior and Administration
NOT_YET_RECRUITINGWarsaw, Poland
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First Department of Cardiology, Medical University of Gdansk, Gdansk, Poland
NOT_YET_RECRUITINGGdansk, Poland
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Fondazione Ricerca e Innovazione Cardiovascolare
NOT_YET_RECRUITINGMilan, Italy
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Heart Institute, Cluj-Napoca
RECRUITINGCluj-Napoca, Romania
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Second Department of Cardiology, Jagiellonian University Medical College, Krakow, Poland
NOT_YET_RECRUITINGKrakow, Poland
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Sibiu County Emergency Clinical Hospital
RECRUITINGSibiu, Romania
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Tan Tock Seng Hospital
NOT_YET_RECRUITINGSingapore, Singapore
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Third Department of Cardiology, Medical University of Katowice
NOT_YET_RECRUITINGZabrze, Poland
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