New injection shows promise for tough lymphoma cases

NCT ID NCT07456371

First seen Mar 11, 2026 · Last updated Jun 19, 2026 · Updated 17 times

Summary

This early-stage trial tests a new biologic drug called PIC1 injection in 18 adults with relapsed or refractory B-cell non-Hodgkin lymphoma. The main goal is to check safety and find the right dose. Researchers will also see if the drug can shrink tumors. It is too soon to know if it will work, but it may offer a new option for patients who have run out of standard treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, 430030, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PIC1 injection (a biologic therapy)

What this could lead to

If successful, this could point toward a new treatment option for patients with hard-to-treat B-cell non-Hodgkin lymphoma.

What could go wrong

This is a very early (Phase 1) and small trial (18 people), so it may not show clear benefit. Side effects are unknown and could be serious.

Conditions

The condition(s) this trial relates to.

B-cell non-Hodgkin lymphoma diffuse large B-cell lymphoma follicular lymphoma high grade B-cell lymphoma mantle cell lymphoma non-Hodgkin lymphoma primary mediastinal large B-cell lymphoma Richter transformation T-cell/histiocyte rich large B cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.