New light therapy could save failing dental implants

NCT ID NCT07191522

Recruiting now Disease control Sponsor: Egas Moniz - Cooperativa de Ensino Superior, CRL Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a light-activated treatment (photodynamic therapy) to standard deep cleaning helps fight infections around dental implants better than cleaning alone. Forty adults with peri-implantitis will receive one of the two treatments, and researchers will measure gum pocket depth, bleeding, and bone loss after 6 weeks. The goal is to find a more effective non-surgical way to preserve implants and prevent implant loss.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: antimicrobial photodynamic therapy (aPDT) using a light-sensitive compound and specific light
What this could lead to: If it works, this could offer a better non-surgical option to treat gum infections around dental implants, potentially saving more implants from being lost.
What could go wrong: This is a small, early-stage trial with only 40 participants and a short 6-week follow-up. The added benefit of photodynamic therapy may be small or not last long, and results may not apply to smokers or people with other health conditions.

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Conditions

The condition(s) this trial relates to.

Peri-Implantitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERI IMPLANTITIS

Contacts and locations

Locations

Egas Moniz School of Health and Science
RECRUITING

Almada, Monte Da Caparica, 2829-511, Portugal

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