Could a pill replace the needle for pain relief?
NCT ID NCT02192151
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study tested an oral form of the painkiller nalbuphine, called PHN131, in 16 healthy adults. The goal was to see how the body absorbs and processes the pill compared to the injected version. Researchers also monitored safety by checking vital signs like blood pressure and heart rate.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- PHN131 (an oral form of nalbuphine hydrochloride)
- What this could lead to
- If successful, this could lead to an oral painkiller that is easier to take than injections.
- What could go wrong
- This is a very early, small study in healthy volunteers, not patients. It only measures how the drug moves through the body, not whether it actually relieves pain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
General Clinical Research Center, Tri-service General Hospital
Taipei, 114, Taiwan
More trials for these conditions
Other studies related to the condition(s) this trial covers.