New pill could ease pain after hemorrhoid surgery

NCT ID NCT02193620

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested an oral soft capsule of nalbuphine, a painkiller, for people recovering from hemorrhoid surgery. 106 adults took either the drug or a placebo for up to 2 days. Researchers measured pain levels and how much extra pain relief was needed. The goal was to see if the oral capsule is safe and effective for post-surgery pain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Nalbuphine (oral soft capsule)
What this could lead to
If it works, this could provide a new oral option for managing pain after hemorrhoid surgery, reducing the need for injections.
What could go wrong
This is a small, early-phase trial (Phase 2/3) with only 106 participants. The results may not apply to everyone, and the drug may not be more effective than existing painkillers.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • General Clinical Research Center, Tri-service General Hospital

    Taipei, 114, Taiwan

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