New pill could ease pain after hemorrhoid surgery

NCT ID NCT02193620

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested an oral soft capsule of nalbuphine, a painkiller, for people recovering from hemorrhoid surgery. 106 adults took either the drug or a placebo for up to 2 days. Researchers measured pain levels and how much extra pain relief was needed. The goal was to see if the oral capsule is safe and effective for post-surgery pain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Nalbuphine (oral soft capsule)

What this could lead to

If it works, this could provide a new oral option for managing pain after hemorrhoid surgery, reducing the need for injections.

What could go wrong

This is a small, early-phase trial (Phase 2/3) with only 106 participants. The results may not apply to everyone, and the drug may not be more effective than existing painkillers.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pain agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • General Clinical Research Center, Tri-service General Hospital

    Taipei, 114, Taiwan