New shot tested to ease pressure on failing livers

NCT ID NCT05490888

Summary

This is a first-in-human study to test the safety and dosing of a new drug called PHIN-214 in adults with liver cirrhosis. The drug is given as a shot under the skin and is designed to reduce high blood pressure in the liver's portal vein, which may help improve kidney function. The study will first test a single dose, then test daily doses for 28 days to find the safest and most effective amount.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Arizona Liver Health

    RECRUITING

    Chandler, Arizona, 85224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cleveland Clinic

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Methodist Health System, Dallas Medical Center

    RECRUITING

    Dallas, Texas, 75203, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Southern California Research Center

    RECRUITING

    Coronado, California, 92118, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tandem Clinical Research

    RECRUITING

    Marrero, Louisiana, 70072, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Texas Liver Institute

    RECRUITING

    San Antonio, Texas, 78215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • VA North Texas Healthcare System

    RECRUITING

    Dallas, Texas, 75216, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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