New drug cocktail shows promise for Tough-to-Treat myeloma

NCT ID NCT03556332

First seen May 08, 2026 ยท Last updated May 08, 2026

Summary

This study tests a combination of four drugs (carfilzomib, lenalidomide, dexamethasone, and daratumumab) given before and after a stem cell transplant for people with multiple myeloma that has come back after previous treatments. The goal is to see if this intensive approach can help more patients achieve complete remission. The trial involves 41 adults aged 18 to 75 who have had 1 to 3 prior treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Contacts and locations

Locations

  • Medical College of Wisconsin (Data Collection Only)

    Milwaukee, Wisconsin, 53226, United States

  • Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (Limited Protocol Activities)

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Westchester (Limited Protocol Activities)

    Harrison, New York, 10604, United States

  • New York University

    New York, New York, 10010, United States

  • Northwell Health

    Manhasset, New York, 11030, United States

  • University of Alabama Comprehensive Cancer Center

    Birmingham, Alabama, 35294, United States

  • Wake Forest University (Data Collection Only)

    Winston-Salem, North Carolina, 27109, United States

Conditions

Explore the condition pages connected to this study.