Real-World watch on ph+ leukemia treatments aims to uncover best paths to remission
NCT ID NCT07684131
First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time
Summary
This study follows adults aged 18 and older who have a specific type of acute lymphoblastic leukemia (Ph+ ALL) and are receiving a combination of targeted drugs (BCR::ABL1 inhibitors) along with chemotherapy, steroids, or antibody therapy. Researchers will track how long patients live and how well the cancer responds over 12 to 36 months. The goal is to gather real-world data on the effectiveness of these treatment combinations.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this observatory could reveal which treatment combinations work best for Ph+ ALL, guiding future care.
- What could go wrong
- This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2024
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Acute Lmphoblastic Leukaemia with Philadelphia chromosome or BCR::ABL1 positive
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Male or female patients ≥ 18 years 2. Philadelphia chromosome or BCR::ABL1 positive acute lymphoblastic leukaemia 3. Treatment with the combination of BCR::ABL1 inhibitors and chemotherapy and/or corticotherapy and/or a monoclonal antibody Exclusion Criteria: 1. Patients deceded and having previously refused data collection 2. Not included in a prospective clinical trial
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
23 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CH Le Mans
RECRUITINGLe Mans, France
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CH St Etienne
NOT_YET_RECRUITINGSaint-Etienne, France
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CH Versailles
RECRUITINGLe Chesnay, France
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CH de Lyon
NOT_YET_RECRUITINGPierre-Bénite, France
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CH de la cote basque
NOT_YET_RECRUITINGBayonne, France
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CHRU de Nancy
NOT_YET_RECRUITINGNancy, France
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CHU Angers
NOT_YET_RECRUITINGAngers, France
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CHU Bordeaux
RECRUITINGBordeaux, France
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CHU Sud Réunion
NOT_YET_RECRUITINGLa Réunion, France
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CHU clermont ferrand
RECRUITINGClermont-Ferrand, France
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CHU de grenoble
NOT_YET_RECRUITINGGrenoble, France
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Centre Antoine Lacassagne
NOT_YET_RECRUITINGNice, 06189, France
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Centre Hospitalier sud francilien
RECRUITINGCorbeil-Essonnes, France
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Chu de Lille
NOT_YET_RECRUITINGLille, France
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Groupe hospitalier sud
NOT_YET_RECRUITINGAmiens, France
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Hopital Cochin
NOT_YET_RECRUITINGParis, France
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Hopital Militaire Percy
NOT_YET_RECRUITINGClamart, France
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Hopital St Louis
RECRUITINGParis, France
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Hopital de Purpan
NOT_YET_RECRUITINGToulouse, France
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Hopital de la conception
NOT_YET_RECRUITINGMarseille, France
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Hopital necker
RECRUITINGParis, France
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ICANS
NOT_YET_RECRUITINGStrasbourg, France
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Institut Paoli Calmettes
NOT_YET_RECRUITINGMarseille, France
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