New tool aims to cut chemo toxicity for seniors with cancer

NCT ID NCT06870617

Recruiting now Symptom relief Sponsor: Abramson Cancer Center at Penn Medicine Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 2 times

Summary

This study tests a practical geriatric assessment (PGA) for adults aged 70+ with advanced cancer. The PGA is a questionnaire completed before a doctor visit, and results are shared with the care team to help guide chemotherapy dosing. Researchers will also track step counts with a FitBit and measure body composition from CT scans to see if these factors relate to side effects. The goal is to make geriatric assessments easier to use and reduce treatment-related toxicity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Practical Geriatric Assessment (PGA) questionnaire and FitBit step monitoring
What this could lead to: If successful, this could make geriatric assessments easier to use in clinics, helping doctors tailor chemotherapy to reduce side effects in older patients.
What could go wrong: This is an early implementation study, not a large trial. The assessment may not change outcomes, and results may not apply to all older cancer patients.

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Conditions

The condition(s) this trial relates to.

cancer metastatic malignant neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED CANCER GERIATRIC ASSESSMENT TOXICITY

Contacts and locations

Locations

Lancaster General Hospital
NOT_YET_RECRUITING

Lancaster, Pennsylvania, 17602, United States
Penn Medicine Princeton Medical Center
RECRUITING

Princeton, New Jersey, 08540, United States
Pennsylvania Hospital
RECRUITING

Philadelphia, Pennsylvania, 19107, United States

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