New hope for Hard-to-Treat endometrial cancer: phase 3 trial launches

NCT ID NCT07578649

NEW Not yet recruiting Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen May 16, 2026 · Last updated May 16, 2026

Summary

This study tests a new experimental drug (PF-08634404) combined with chemotherapy against an approved drug (pembrolizumab) plus chemotherapy for adults with advanced or recurrent endometrial cancer that has a working DNA repair system (pMMR). About 600 women will be randomly assigned to one of the two treatment groups. The goal is to see if the new combination helps keep cancer from growing longer than the current standard treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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