New hope for Hard-to-Treat endometrial cancer: pfizer launches phase 3 trial

NCT ID NCT07578649

Not yet recruiting Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen May 16, 2026 · Last updated May 22, 2026 · Updated 2 times

Summary

This study tests a new experimental drug (PF-08634404) combined with chemotherapy against an approved drug (pembrolizumab) plus chemotherapy in adults with advanced or recurrent MMR-proficient endometrial cancer. About 600 women will be randomly assigned to one of two groups and receive treatment through IV infusions. The goal is to see if the new combination helps delay cancer growth or improve survival.

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