New drug trial targets Hard-to-Treat cancers
NCT ID NCT05983133
First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 24 times
Summary
This early-stage study tests a new drug, PF-08046052/SGN-EGFRd2, in people with advanced solid tumors that cannot be removed or have spread. The main goal is to check safety and side effects. About 68 participants with colorectal, lung, head/neck, or pancreatic cancer will take part. The study will first find the right dose, then see if the drug works.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Atrium Health Wake forest Baptist
Winston-Salem, North Carolina, 27157, United States
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
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Huntsman Cancer Hospital, University of Utah
Salt Lake City, Utah, 84112, United States
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Huntsman Cancer Institute, University Of Utah
Salt Lake City, Utah, 84112, United States
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John Theurer Cancer Center at Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
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Karmanos Cancer Institute
Detroit, Michigan, 48201, United States
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Karmanos Cancer Institute Weisberg Cancer Treatment Center
Farmington Hills, Michigan, 48334, United States
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MD Anderson Cancer Center - University of Texas
Houston, Texas, 77030, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Moffitt Cancer Center McKinley Hospital
Tampa, Florida, 33612, United States
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Providence Cancer Institute Franz Clinic
Portland, Oregon, 97213, United States
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Providence Portland Medical Center
Portland, Oregon, 97213, United States
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Ronald Reagan UCLA Medical Center
Los Angeles, California, 90095, United States
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Santa Monica UCLA Medical Center & Orthopaedic Hospital
Santa Monica, California, 90404, United States
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The Christie NHS Foundation Trust
Manchester, M20 4BX, United Kingdom
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The University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
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UCLA Hematology/Oncology
Los Angeles, California, 90095, United States
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UCLA Hematology/Oncology - Santa Monica
Santa Monica, California, 90404, United States
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University College London Hospital, NIHR UCLH Clinical Research Facility
London, W1T 7HA, United Kingdom
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University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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University of Iowa
Iowa City, Iowa, 52242, United States
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University of Utah
Salt Lake City, Utah, 84112, United States
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Wake Forest Baptist Medical Center / Wake Forest University
Winston-Salem, North Carolina, 27157, United States
Conditions
Explore the condition pages connected to this study.